Alvedia

• until 24 hours after collection

• Haemostasis disorders : thrombocytopenia, thrombopathias, coagulopathies
• Anaemia, hemorrhage
• Renal failure
• Liver failure
• Septic shock

• In anaemic normo-volumiques patients, risk of volume overload

• separated for less than 4 h use within 24 h

Frozen Plasma

• 
  frozen within 6 to 8h

• Hypovolemia (trauma, surgical resuscitation)
• Acquired or hereditary deficiency of coagulation factors
• Antivitamin K poisoning
• Hypoproteinemia
• Pancreatitis
• Antioxydant properties

• Because of the short half-life of coagulation factors, several transfusions may be necessary

• Erythrocyte suspension  obtained after centrifugation: 2000 rpm for 30 min, or 5000 rpm for 5 min
• 50% < Ht < 80%

• Anaemia

• High viscosity reduces administration speed
• Dilution with NaCl 0,9% (0,5mL per mL of concentrate)