Gel Test Canine DAT
A Direct Antiglobulin Test (DAT) or Coombs Test is performed to detect the presence of antibodies against red blood cells. It is used in the diagnosis of Immune- Mediated Hemolytic Anemia (IMHA). IMHA is the most common cause of hemolytic anemia in dogs.
There are 2 forms of IMHA:
• The first one is idiopathic IMHA (or primary IHMA) which is probably due to a dysregulation of the immune system.
• The Second one (secondary IMHA) is associated with several diseases such as infection diseases (virus, bacteria, parasitic…) or haemopathy or auto immune diseases (lupus). Drug reactions could also induce a secondary IMHA
Our canine DAT Gel Test (or Coombs Test) is based on an individual Gel Test microtube filled with a mixture of gel and specific canine Antiglobulin reagent that will detect the presence of immunoglobulins (IgG & IgM) and/or C3 components binding to the red blood cells surface. A positive result indicates an in vivo sensitization with the presence of auto-immune antibodies.
Reliable in case of low pcv (anemia) Thanks to the sensitivity of our specific monoclonal antibodies, even with a very low PCV (hematocrit) will allow you to obtain a reliable Feline blood typing result.
Thanks to our specific membrane technology, the agglutinated red blood cells (RBCs) will be retained at the bottom of the membrane whereas non agglutinated RBCs will continue to migrate to the top of the membrane.