Importance of crossmatching

Cats have one main blood group system named AB system with 3 types: blood type A which is the most frequent, blood type B and blood type AB. The presence of naturally occurring alloantibodies in type A and in type B cats requires that blood typing must be performed prior to ALL blood transfusions to avoid an acute hemotytic transfusion reaction. It is now well established that cats possess other blood group systems such as Mik antigen or other unknown systems. This test allows detection of incompatibilities associated with the AB blood group system, Mik, Feline Erythrocyte Antigens (FEA), and other unidentified red blood cell alloantibodies.

According to recent publications, it is now highly recommended to perform a Crossmatch Test (XM) in cats before the first transfusion. 

Benefits

• 15 minutes procedure.
• All material included.
• Time saving.
• Easy handling.
• Reliable results.
• Easy interpretation.

Our technology

Our Feline crossmatch test (major and/or minor) is based on an immuno-chromatographic technology that will detect the presence of alloantibodies binding to the red blood cells (RBCs) surface after a mismatched transfusion or naturally occurring alloantibodies.

PDF : BeST Individual test XM Feline

PDF : BeST LabTest XM Feline

BeST XM Feline (Crossmatch Test)  – BQT-XM-F –  1 TEST (individual packaging)

BeST XM LabTest Feline (Crossmatch Test) – BLT-XM-F – 10 TESTS / BOX (bulk packaging)

• It is MANDATORY to blood type both the donor and the recipient for the AB blood group system before performing a Feline XM Test.
• This test allows detection of incompatibilities associated with the AB blood group system, Mik, Feline Erythrocyte Antigens (FEA), and other unidentified red blood cell alloantibodies.
• This test is used to detect alloantibodies after a mismatched transfusion or naturally occurring alloantibodies.
• Positive XM reactions may be observed in IMHA patients due to circulating autoantibodies present in the recipient plasma.
• Cats may rapidly develop alloantibodies following a transfusion. A XM is recommended before any transfusion, even if a previous transfusion was compatible.
• Test results must be interpreted in conjunction with the clinical and therapeutic context.
• The use of properly stored and well-preserved red blood cells is essential for reliable test performance and accurate result interpretation: samples showing hemolysis, bacterial contamination, or poor preservation may lead to inaccurate results.
• In Minor XM tests, weak false-positive reactions may occasionally occur when frozen-thawed donor plasma contains residual fibrin aggregates. If visible fibrin filaments are observed in the plasma sample, a centrifugation step is recommended.